Editor: Draco Copper | Tactical Investor

Random Thoughts

The Gold bugs and Gold experts must be going through hell; almost seven years later and the Gold Bull Market refuses to follow the path these individuals have laid out for it. Proclamation after proclamation has failed, and the detested dollar much to their angst and surprise has continued to trend higher. Inflation has not taken off as they expected; well at least based on the distorted figures the government issues. The masses believe this data is real and that is all that matters in the end. Bull Run for Gold Sheer Fantasy or is it forming the base for the next Run

Could THIS be the end of daily injections for diabetics: Possibly

A single injection may soon give diabetics weeks of glucose control rather than having to self-administer as frequently as every day, new research reveals.

Researchers discovered a new technology may improve on existing drugs that aim to better glucose control.

By forming a gel that slowly dissolves under our body heat, the new therapy extends glucose control by up to three times in non-human primates, the study found.

The researchers hope the treatment could last even longer in humans as we have a slower metabolism than most other animals and therefore break drugs down slower.

Standard type 2 diabetes therapies have to be administered at least twice a day, while the longest-acting glucose control treatment on the market, known as dulaglutide, still requires a once-weekly injection.

In primates, the technology provided glucose control for up to three times longer than existing treatments.

It was also tested in mice.

By limiting the number of injections a diabetic needs to control their glucose levels, the researchers hope this new technology will improve patient compliance.

The results were published in the journal Nature Biomedical Engineering.

Current type 2 diabetes treatments slow the release of insulin to control blood sugar levels, however, the responsible molecule is quickly cleared from the body. Full Story

Holy grail’ of insulin pill

Researchers have created a pill which could dramatically transform the way diabetics keep their blood sugar levels in check.

It is hoped the oral delivery of insulin could eliminate the need for painful injections, which up to 40 million people living with type 1 diabetes require once or twice a day.

In research published in the journal Proceedings of the National Academy of Sciences, researchers at the Harvard John A Paulson School of Engineering and Applied Sciences (SEAS) outlined how they found a way to deliver insulin orally.

They said the pill could also mitigate many of the disease’s life-threatening side effects that result from patients avoiding insulin therapy, which is administered from an injection under the skin or delivered by an insulin pump.

“But many people fail to adhere to that regimen due to pain, phobia of needles, and the interference with normal activities,” said Samir Mitragotri and Hansjorg Wyss, two of the report’s authors. “The consequences of the resulting poor glycemic control can lead to serious health complications.”

“Once ingested, insulin must navigate a challenging obstacle course before it can be effectively absorbed into the bloodstream,” said Mr Mitragotri.

“Our approach is like a Swiss army knife, where one pill has tools for addressing each of the obstacles that are encountered. Full Story

This pill could end the need for diabetics’ daily injections

The new approach carries insulin in an ionic liquid comprised of choline and geranic acid that is put underwaycapsule with an acid-resistant enteric coating. In research published in the journal Proceedings of the National Academy of Sciences, researchers at the Harvard John A Paulson School of Engineering and Applied Sciences outlined how they found a way to deliver insulin orally.

If trials are successful, it could mean many diabetics are freed from the burden of daily injections to make up for the body’s inability to make enough insulin. “Once ingested, insulin must navigate a challenging obstacle course before it can be effectively absorbed into the bloodstream,” said Samir Mitragotri, Professor at the Harvard University.

The major stumbling block has been the fact that insulin is easily destroyed by digestive juices in the stomach before it can get into the bloodstream. Full Story

Could This Be End of Daily Injections for Diabetics

Random Thoughts

Could THIS be the end of daily injections for diabetics: Possibly

Holy grail’ of insulin pill

This pill could end the need for diabetics’ daily injections

Other stories of Interest